The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms complications lupus erythematosus systemic allergy extraarticular gastrointestinal humoral hypersensitivityreaction immunity msk mucocutaneous musculoskeletal pan polyarteritisnodosa ra rheumatoidarthritis type3
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Erythematosus (SLE ... Serum sickness #TypeIII ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... Erythematosus #SLE ... Complications #pathophysiology ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Livedo Reticularis, Vasculitis ... #pathophysiology ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Musculoskeletal Manifestations ... Erythematosus #SLE ... Complications #pathophysiology ... signs #symptoms #diagnosis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
classical pathway (see ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
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