The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk signs symptoms acute acs allergy causes classification compartmentsyndrome complications differential disruptors endocrinology excess femoralhead femur fracture genetics gh
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk #orthopedics ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Sacral compression fracture ... bilateral rami fractures ... Grades #Grading #Orthopedics ... complications #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... #msk #orthopedics ... differential #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Incr Skeletal fractures ... #PraderWilli #Syndrome ... #genetics #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... Posterior Cord Syndrome ... #diagnosis #pathophysiology ... symptoms #msk #orthopedics
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment Syndrome ... bleeding tendency/fracture ... CompartmentSyndrome #ACS #pathophysiology ... #orthopedics
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... Acne • Coarse features ... endocrinology #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... chondrocytes at fracture ... #Stages #Orthopedics ... #msk #Staging #pathophysiology
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