The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
palpation - Vasculitic ... Temporal #Arteritis #Pathophysiology ... Signs #Symptoms #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Complications #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... Cutaneous small vessel vasculitis ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
PolyarteritisNodosa #Pathophysiology ... Signs #Symptoms #Vasculitis
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
CranialArteritis #Pathophysiology ... Symptoms #Diagnosis #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... RheumatoidArthritis #RA #pathophysiology
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Criteria #Diagnosis #Pathophysiology ... Signs #Symptoms #Vasculitis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
PM #Diagnosis #Pathophysiology ... Signs #Symptoms #Vasculitis
Diabetic Nephropathy: Pathogenesis - Metabolic Pathway - Hemodynamic Pathway #Diabetic #Nephropathy #Diabetes #pathophysiology
Nephropathy #Diabetes #pathophysiology
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