The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
, and/or limbs caused ... restlessness #AntiPsychotics ... #pharmacology #diagnosis ... #psychiatry
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... Schizophrenia #pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, tachycardia, nausea ... AlcoholUseDisorder #EtOH #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
SUI or UUI not caused ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology ... #Diagnosis
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Manic #Secondary #Causes ... #Differential #Diagnosis ... #Pathophysiology ... #Psychiatry
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses ... #Varicocele #Pathophysiology ... Signs #Symptoms #Urology ... #Diagnosis
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
hearing loss, nausea ... #Mastoiditis #pathophysiology ... signs #symptoms #diagnosis ... #otology