The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology signs psychiatry sideeffects inhibitors alcohol alcoholusedisorder anticonvulsants antipsychotics benzodiazepine bzd mechanism mechanisms moodstabilizers opiate opioid serotonin serotoninnorepinephrine snris
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to effects of EtOH ... exacerbated by EtOH ... • Withdrawal ... symptoms - ... Diagnosis #Signs #Symptoms
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Pathophysiology #Pharmacology ... Diagnosis #Signs #Symptoms
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Note: Opioid withdrawal ... life-threatening (exceptions being ... combined with withdrawal ... rapid iatrogenic withdrawal
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Pathophysiology #Pharmacology ... Diagnosis #Signs #Symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Allergic reaction -> Benign ... decr intake -> Withdrawal ... Pathophysiology #Psychiatry #Pharmacology
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Extrapyramidal Symptoms ... AntiPsychotics #FirstGeneration ... #SideEffects #pharmacology
Alcohol Withdrawal: Clinical Findings and Complications The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Symptoms typically ... >2 days after EtOH ... Seizures - Usually begin ... #EtOH
Benzodiazepine (BZD) withdrawal: clinical findings and complications • Activation of ACC and OFC -> Feelings of
Benzodiazepine (BZD) withdrawal ... Asthma. or sense of being ... Benzodiazepine #BZD #withdrawal ... #pharmacology # ... diagnosis #signs #symptoms
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