The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
decr intake -> Withdrawal ... MoodStabilizers #Mechanism #SideEffects ... #Pathophysiology ... #Psychiatry #Pharmacology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... symptoms are more acute ... The less acute behavioral ... #Opiate #Pathophysiology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine (BZD) withdrawal ... clinical findings and complications ... Activity -> Incr BP ... #pharmacology # ... pathophysiology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
limbs caused by chronic ... bradykinesia/akinesia • Acute ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive ... vasoconstrictive • Acute ... and chronic vasospasm ... #Retinopathy #pathophysiology ... signs #symptoms #complications
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
-15, IL-17) -> Chronic ... Hydronephrosis, Acute ... or chronic renal ... bladder stones #BPH ... Hyperplasia #Prostate #Pathophysiology
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Clinical Findings and Complications ... Alcohol withdrawal ... Generalized Tonic-Clonic ... #Pathophysiology
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
Signs / Symptoms / Complications ... inflammation • Acute ... Mastoiditis • Chronic ... Cholesteatoma #MiddleEar #pathophysiology ... signs #diagnosis #complications