The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis psychiatry pharmacology signs endocrinology inhibitors anticonvulsants antipsychotics anxiety behavioraldisorder feedbackloop firstgeneration gh glucocorticoids growthhormone hyperthyroidism macroadenoma masseffects mechanism mechanisms
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Signs / Symptoms ... #Macroadenoma #SideEffects ... endocrinology #mnemonic #GLFTAP ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Anticonvulsants #MoodStabilizers ... #Mechanism #SideEffects ... #Pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #SideEffects ... Diagnosis #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #SideEffects ... Diagnosis #Signs #Symptoms
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... endocrinology #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... endocrinology #pathophysiology ... #pituitary
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
on hypothalamus/pituitary ... #Osteoporosis #pathophysiology ... #signs #symptoms
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Hypothalamus -> Pituitary ... Extrapyramidal Symptoms ... FirstGeneration #Mechanisms #SideEffects
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
and hypothalamic-pituitary-adrenal ... trigger Physical Symptoms ... Psychological Symptoms ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms
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