The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis 21hydroxylasedeficiency ankylosingspondylitis centralretinalartery chondrocalcinosis chronic closedangle cppd crao criteria extraarticular genetics glaucoma hypertensive kawasaki keratoconus manifestations occlusion pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD ... pathophysiology #genetics #endocrinology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... • The disease ... damage & blindness Signs ... / Symptoms / Complications ... pathophysiology #ophthalmology
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... hands & feet Signs ... /Symptoms/Complications ... : - Coronary Arteritis ... #Kawasaki #Disease
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
rubbing • Atopic diseases ... > Keratoconus Signs ... / Symptoms / Complications ... • Rizutti's Sign ... pathophysiology #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... trucking" • Acute ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... Pathogenesis and Joint diseases ... • Non-specific Acute-phase ... Extra-articular signs ... #symptoms #diagnosis
Psoriatic Arthritis: Complications • Ocular - Inflammation of middle layer of the eye (the uvea, which
Psoriatic Arthritis ... : Complications ... Cardiac - Valvular disease ... pathophysiology #diagnosis #signs ... #symptoms #Complications
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
CPPD) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... polyarticular arthritis ... #Signs #Symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Inflammatory Bowel Disease ... - Inflammation acute ... Manifestations #Complications ... pathophysiology #diagnosis #signs ... #symptoms
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