The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Patient's immune system ... cells recruited Complications ... : • Acute Asthma ... conjunctivitis • Anaphylaxis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Acute onset of skin ... exposure to known allergen ... symptoms in the acute ... / Symptoms / Complications
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Vasculitis -> Acute ... distension #Systemic ... Gastrointestinal #Complications ... pathophysiology #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Osteoporosis #Systemic ... Musculoskeletal #Complications ... pathophysiology #signs
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... • Non-specific Acute-phase ... deviation, etc • Systemic ... Extra-articular signs ... pathophysiology #signs
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Takayasu’s Arteritis ... , Incr risk of Acute ... Syndrome - >10mmHg systolic ... #Takayasus #Arteritis ... Vasculitis #Diagnosis #Signs