The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... /Symptoms: - Pretibial ... GravesDisease #pathophysiology ... #signs #diagnosis
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
Occlusion #CRVO #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... and Symptoms ... Radiculopathy #MSK #diagnosis ... #signs #symptoms ... #pathophysiology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... CubitalTunnel #Syndrome #Diagnosis ... #pathophysiology ... #signs #symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry ... #criteria
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Criteria - Fever ... #Criteria #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... erosion and gum disease ... inducing vomiting #BulimiaNervosa ... #pathophysiology ... #diagnosis #signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #differential #diagnosis ... #signs #symptoms