The Calgary Guide to Understanding Disease @TheCalgaryGuide
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allergy diagnosis symptoms gh growthhormone pituitary 21hydroxylasedeficiency 21ohd agammaglobulinemia anaphylaxis diabetes dka endocin excess feedbackloop genetics glftap gravesdisease hyperthyroidism macroadenoma
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
TypeIII #Type3 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
#Type2 #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... phase symptoms Signs ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis ... #signs #symptoms
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
#TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... confusion coma #DiabeticKetoacidosis ... #DKA #pathophysiology ... #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
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