The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
lupus erythematosus ... (SLE) Signs / ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... into the limbic system ... cause the Positive Symptoms ... Schizophrenia #pathophysiology ... #signs #psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
autononomic nervous system ... Psychological Symptoms ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Anorexia Nervosa: Signs and Symptoms
Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
Anorexia Nervosa: Signs ... and Symptoms Binge ... irritability #AnorexiaNervosa ... #pathophysiology ... #symptoms #psychiatry
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
neurotransmitter systems ... athletics) #AnorexiaNervosa ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
mortality rates of all psychiatric ... binge-purge subtype #AnorexiaNervosa ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Disorder (SAD) - Pathophysiology ... Autonomic Nervous System ... BehavioralDisorder #SAD #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry