The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs ophthalmology orthopedics pediatrics peds syndrome 21hydroxylasedeficiency 21ohd achilles adhesivecapsulitis bulimianervosa caudaequina chronic closedangle endocrinology erythematosus femoralhead frozenshoulder
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... lateral hip Signs/Symptoms ... /Complications: ... #msk #diagnosis ... pathophysiology #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... /Complications: ... Incr Skeletal fractures ... PraderWilli #Syndrome #genetics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... /Complications: ... diagnosis #signs #symptoms ... pathophysiology #msk
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... pathophysiology #genetics
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... lights are a key symptom ... • Significant cause ... most frequent cause ... / Complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... BRB breakdown causes ... diagnosis #signs #symptoms ... #complications
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Symptoms can take ... are more acute ... The less acute behavioral ... Gastrointestinal distress (nausea
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