The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder ... • Humeral head anterior ... Diagnosis #signs #symptoms ... #msk #orthopedics ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
acetabular wall • Anterior ... femoral head onto anterior ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... PraderWilli #Syndrome #genetics ... #pathophysiology ... #peds #pediatrics
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Neurotic personality Genetics ... PanicDisorder #Anxiety #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #signs #psychiatry
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings • Anterior ... Cord Syndrome -> Anterior ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Disorder (SAD) - Pathophysiology ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Gender: F > M • Genetics ... functioning of the anterior ... AnorexiaNervosa #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry #RiskFactors