The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs mnemonic psychiatry criteria peds genetics gh growthhormone obsessivecompulsive ocpd pituitary 21hydroxylasedeficiency 21ohd alzheimersdisease amsuicide antisocial aspd avoidant
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
ObsessiveCompulsive #PersonalityDisorder ... Psychiatry #Signs #Symptoms
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... BPD #Borderline #PersonalityDisorder ... Criteria #Signs #Symptoms
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology ... #peds #pediatrics
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
#Schizotypal #PersonalityDisorder ... Criteria #Signs #Symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs / Symptoms ... pathophysiology #geriatrics ... diagnosis #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... pathophysiology #peds #pediatrics
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
diagnosis #signs #symptoms ... #endocrinology
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