The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis psychiatry sideeffects gh growthhormone inhibitors mnemonic pharmacology criteria feedbackloop glftap hyperthyroidism macroadenoma masseffects narcissistic npd obsessivecompulsive ocpd overproduction
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Selective Serotonin ... Syndrome: - ... SSRI Withdrawal Syndrome ... Psychiatry #Diagnosis #Signs ... #Symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... GH excess prior ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
Hypotheses • Serotonin ... of postsynaptic serotonin ... ObsessiveCompulsive #PersonalityDisorder ... Diagnosis #Psychiatry #Signs ... #Symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... lipid • GH excess ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... Nausea, Vomiting Serotonin ... Syndrome - Potentially ... Psychiatry #Diagnosis #Signs ... #Symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... Signs / Symptoms ... #SideEffects #endocrinology
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
- Entitlement, Excess ... #Narcissistic #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Syndrome: Variable ... #Syndrome #Pathophysiology ... Psychiatry #Diagnosis #Signs ... #Symptoms
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