The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Decr Protease inhibitors ... rubbing • Atopic diseases ... Signs / Symptoms ... Ring • Munson's sign ... • Rizutti's Sign
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... SSRIs #Serotonin #Inhibitors ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... #Criteria #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... trucking" • Acute ... ophthalmology #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... • Non-specific Acute-phase ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
CPPD) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... #Signs #Symptoms ... Pathophysiology #Diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
- Sickle-cell disease ... affected) - Acute ... hypolucency "Crescent sign ... pathophysiology #diagnosis ... #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Inflammatory Bowel Disease ... - Inflammation acute ... pathophysiology #diagnosis ... #signs #symptoms