The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... • Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #SideEffects
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #SideEffects
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mood Stabilizers: Mechanism ... Stevens-Johnson Syndrome ... MoodStabilizers #Mechanism ... #SideEffects #Pathophysiology
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
Complications Continence mechanisms ... impairment Continence mechanisms ... irritable bowel syndrome ... Incontinence #geriatrics #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... #PraderWilli #Syndrome ... #genetics #pathophysiology ... #peds #pediatrics
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
continue growing (mechanism ... growth (this is one mechanism ... Polycystic Ovarian Syndrome ... #MenstrualCycle ... #OvarianCycle #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
slide for full mechanisms ... #OtitisMedia #pathophysiology ... symptoms #signs #peds
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment Syndrome ... local signalling mechanisms ... CompartmentSyndrome #ACS #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
puberty (unclear mechanisms ... #UterineCycle #MenstrualCycle ... #OvarianCycle #pathophysiology
Shoulder Impingement Syndrome (SIS): Signs and Symptoms

Repetitive Overhead Activity, Scapular Dyskinesis -> Scapulohumeral mechanics become altered
Shoulder Impingement Syndrome ... Scapulohumeral mechanics ... Shoulder Impingement Syndrome ... #Impingement #Syndrome ... symptoms #msk #pathophysiology