The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms complications pseudogout acute adhesivecapsulitis agammaglobulinemia alzheimersdisease avascularnecrosis bakerscyst bulimianervosa caudaequina cecs centralretinalartery chronicexertional compartmentsyndrome crao dementia differential endocrinology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... and/or x-ray - CPPD ... #Pseudogout #CPPD ... #Disease #Signs ... Pathophysiology #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... ) Deposition Disease ... e.g., wrist) #Chondrocalcinosis ... #Disease #Signs ... Pathophysiology #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... Alzheimer's (99% of cases ... chromosome 21) Signs ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis ... #symptoms #signs
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Cardiovascular disease ... Overproduction #diagnosis ... #signs #symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
sensory • Before diagnosis ... intervertebral disc disease ... MeralgiaParesthetica #MSK ... #differential #diagnosis ... #signs #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... 40% of patients diagnosed ... history of the disease ... Signs of immunodeficiency ... to produce all classes
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