The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... #Syndromes #diagnosis ... #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
(uncommonly injured ... LowAnkleSprain #Sports ... #MSK #orthopedics ... Grading #Grades #Diagnosis ... #pathophysiology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... > Stiffness is short-lived ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
RICE: Mechanism of Action
Rest (weight bearing or stressful motion discontinued)
Ice (applied to injury)
Compression (wrap applied to
Ice (applied to injury ... wrap applied to injured ... heart) #RICE #Sports ... #pathophysiology ... #mechanism #MSK
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Ligament (PCL) Injury ... Some sort of end ... PosteriorCruciateLigament #PCL #Injury ... #MSK #Sports #pathophysiology ... classification #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
• Large lumbar degenerative ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Related Macular Degeneration ... - Faded/blind spots ... MacularDegeneration #pathophysiology ... #ophthalmology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
around the hip • Degeneration ... Trendelenburg #Gait #pathophysiology ... symptoms #signs #diagnosis ... #msk
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs