The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology signs symptoms sle erythematosus caudaequina comparison degenerative gastrointestinal incontinence inflammatory jointdisease jointpain manifestations mixed mucocutaneous musculoskeletal pagetsdisease syndrome urinary
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... Gastrointestinal #Complications ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #SLE #MSK #Musculoskeletal ... #Complications ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... signs #symptoms #complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
is oftentimes systemic ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incr PVR if a complication ... SUI or UUI not caused ... Signs #Symptoms #Urology ... #Diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... pathophysiology #diagnosis ... signs #symptoms #complications
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