The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms complications sle staging adhesivecapsulitis aseptic comparison degenerative disruptors erythematosus evaluation fracture frozenshoulder healing history inflammatory jointdisease jointpain
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... Erythematosus #SLE #MSK ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... side) Second Stage ... movement) Third Stage ... pathophysiology #diagnosis ... #staging #msk
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... are connected) Stage ... hearing loss, nausea ... signs #symptoms #diagnosis ... #otology
Mental Status Exam (MSE) Note: The MSE is a "snapshot" of a patient at a specific time. You
Mental Status Exam ... (MSE) Note: The ... clothing, appears stated ... , the symptoms caused ... #psychiatry #diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Lots of fluid, takes ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #Orthopedics #msk ... pathophysiology #diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... Skull expansion causes ... pathophysiology #diagnosis
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