The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile Dysfunction ... Psychogenic Erectile Dysfunction ... #Erectile #Dysfunction ... Pathophysiology #Urology
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
disturbance arising from dysfunctional ... Structural model: Dysfunction
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... #orthopedics #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Executive planning dysfunction ... concentration • Motor dysfunction
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vertigo, Sexual Dysfunction
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
bladder/bowel dysfunction
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
• Hypothalamic dysfunction
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
defects (i.e. dysfunction
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Compensatory muscular dysfunction
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
Pathophysiology #Urology