The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs symptoms psychiatry anxiety benign bph endocrinology pediatrics peds prostate prostatic riskfactors vasculitis 21hydroxylasedeficiency acute affectivedisorder agammaglobulinemia anorexianervosa arteritis behavioraldisorder
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Complications: • Gonadal hypoplasia ... PraderWilli #Syndrome #genetics ... #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications Aging -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic Hyperplasia ... cell nuclei -> Hyperplasia ... smooth-muscle hyperplasia ... #Prostate #Pathophysiology ... #Pharmacology #Urology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... GravesDisease #pathophysiology ... symptoms #signs #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
not proven) - Genetic ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Pathogenesis of Anxiety Disorders Anxiety Disorders: A maladaptive emotional state causing fear, worry, and excessive stress, characterized by:
reporting rates) • Genetics ... Anxiety #Disorders #Pathophysiology ... #diagnosis #psychiatry
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... Benign #Prostatic #Hyperplasia ... #Prostate #Pathophysiology ... #Urology #Signs ... #Symptoms #Diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
predisposition - Various genetic ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Priapism: Pathogenesis - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
#Priapism #Pathophysiology ... #Urology #Diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Genetic Predisposition ... Agammaglobulinemia #XLinked #pathophysiology
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