The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Prolactin #PRL #FeedbackLoop ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
GrowthHormone #GH #FeedbackLoop ... #endocrinology ... #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
inflammation #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
and rigidity Endocrinologic ... #Dysfunction #Pathophysiology ... #Urology #Diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
bladder stones #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Activity -> Incr BP ... BZD #withdrawal #pharmacology ... #pathophysiology