The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology symptoms allergy classification gastrointestinal hypersensitivity hypersensitivityreaction immunology manifestations msk mucocutaneous musculoskeletal primary reactions sjogrens syndrome type3 typeiii types
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... #Complications ... pathophysiology #signs
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... complexes • Ex: Systemic ... Lupus Erythematosus ... Classification #Diagnosis #Definitions
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Lupus #Erythematosus ... #Complications ... pathophysiology #signs
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis #Signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous ... pathophysiology #diagnosis #signs ... #symptoms #complications
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