The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms arteritis giantcell growthhormone pituitary complications cranialarteritis excess feedbackloop giantcellarteritis glftap macroadenoma masseffects mnemonic overproduction polymyalgiarheumatica sideeffects
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... visual acuity • Bitemporal ... signs #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH ... #FeedbackLoop #endocrinology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... palpation - Vasculitic ... #GiantCell #Temporal ... Signs #Symptoms #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Giant Cell (Temporal ... palpation - Temporal ... #GiantCell #Temporal ... Symptoms #diagnosis #Vasculitis
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... dysfunction • Bitemporal ... #SideEffects #endocrinology
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Weight Loss #Temporal ... Symptoms #Diagnosis #Vasculitis
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