G jones @newfmd on GrepMed

Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism • Hypercalcemia (in the setting of long-standing secondary hyperparathyroidism) (e.g. Renal Failure, Post-Renal Transplant) Familial Hypocalciuria Hypercalcemia • Autosomal Dominant Calcium Receptor Mutation (CaSR) • Other Familial Hypercalcemias (e.g. MEN) Drug Side Effects • Thiazide Diuretics • Lithium • Vitamin A/lsotretinoin Malignancy • PTH-Related Peptide (e.g. Breast, Kidney, Lung) • Cytokine-Mediated Bone Resorption (e.g. Multiple Myeloma, Lymphomas) Metastatic Bone Disease Vitamin D Related • Excess Vitamin D/Calcitriol Intake • Unregulated Conversion of 25-OH D3 to 1,25-(OH)2D3 (e.g. Granulomatous Disease, Lymphoma) Other • Excess Calcium Intake (e.g. Milk Alkali) • Immobilization • Adrenal Insufficiency • Thyrotoxicosis • Paget's Disease #Hypercalcemia #Differential #Diagnosis #Algorithm #Endocrinology #HighCalcium

Management of Hypercalcemia Bryan Ulrich @BryanCUlrich #Hypercalcemia #Management #Algorithm

Infectious Diarrhea - Laboratory Testing Clostridium difficile Salmonella enterica, Shigella spp, Campylobacter spp Salmonella enterica serovars Typhi and Paratyphi (enteric fever) Shiga toxin–producing Escherichia coli Yersinia spp, Plesiomonas spp, Edwardsiella tarda, Staphylococcus aureus, E. coli (enterotoxigenic, enteroinvasive, enteropathogenic, enteroaggregative) Clostridium perfringens Bacillus cereus, S. aureus Clostridium botulinum Entamoeba histolytica; Blastocystis homini, Dientamoeba fragilish; Balantidium coli; Giardia lamblia; nematodes (generally not associated with diarrhea) including Ascaris lumbricoides, Strongyloides stercoralisi, Trichuris trichiura, hookworms; cestodes (tapeworms); trematodes (flukes) E. histolytica G. lamblia Cryptosporidium spp Cyclospora cayetanensis, Cystoisospora belli Microsporidia (now classified as a fungus) Calicivirus (norovirus, sapovirus); enteric adenovirus; enterovirus/parechovirus; rotavirus Rotavirus, enteric adenovirus Enteric adenovirus; enterovirus/parechovirus Cytomegalovirus #Infectious #Diarrhea #diagnosis #differential #Laboratory #Testing

Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage forms and conversion of IV to PO anti-infectives. #pharmacology #antibiotics #medications #table #treatment #drugs #pharmacotherapy

Mechanism of antibiotic drug resistance #pharmacology #antibiotics #review #medications

Mass General Hospital COVID19 Critical Care Treatment Guide #COVID19 #CriticalCare #Treatment #MGH #Management #Coronavirus #SARSCOV2

MGH Sedation protocol for mechanically ventilated COVID-19 patients #Sedation #Analgesia #Protocol #COVID19 #CriticalCare #Treatment #MGH #Management #Coronavirus #SARSCOV2

Running out of Analgesia and Sedation Medications due to #COVID19? Anand Swaminathan, MD has put together a list of possible options in REBEL Review #97: Sedation and Analgesia Alternative Medications #management #covid19 #treatment #sarscov2 #criticalcare #coronavirus #medications #sedation #sedative #analgesia #pharmacology #alternatives #Drugs

PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction. PDE5 inhibitors enhance an erection that is partially developing as a result of effective sexual stimulation and mental sexual arousal. Drug interactions with PDE5 inhibitors include alpha blockers and CYP3A4 inhibitors - which can be used concomitantly with caution - e.g. at lower doses. PDE5 inhibitors should not be used with nitrates due to serious and potentially fatal hypotension - and should be separated by 12 - 48 hours (depending on the drug). #pharmacology #comparison #treatment #medications #dosing #drugs #table #pharmacotherapy

Pharmacologic Treatment of Hyperthyroidism #Hyperthyroidism #Treatment #Management #Pharmacology #Medications #Comparison #Table #Endocrinology #AAFP #Propylthiouracil #Methimazole

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