Dr. Jorge Cortés @jcortesizaguirr
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diagnosis differential causes management workup cardiology hematology hepatology abnormal algorithm ana antibodies antibody antineutrophil antinuclear ascites carcinoma chagas coagulation cushings
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
connective tissue disease ... 80-90%) > MPO - ANCA ... 90% • Anti-GBM disease ... - MPO>PR3 - ANCA ... #rheumatology #diseases
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... Early liver disease ... typically prolong aPTT ... may prolong the aPTT ... Prolonged PT and aPTT
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
cases: INR/PT, aPTT ... (liver disease, ... function test, ANA ... bypass), LFT (liver disease
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Chagas Disease - ... Summary Chagas disease ... an infectious disease ... 70-80% have no disease ... → 20-30% have disease
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
) Peptic Ulcer disease ... rarely in Cushing's disease ... 2) Cushing's disease ... • In Cushing's disease
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
locally advanced disease ... of metastatic disease ... of metastatic disease
Causes of Granulomatous Liver Diseases - Differential Diagnosis Infections (Bacterial, Viral, Fungal, Parasitic) Malignancy Autoimmune Drugs/Toxins Others #Granulomatous #Liver #hepatic #granulomas #Differential
Granulomatous Liver Diseases
Causes of Encephalopathy - Differential Diagnosis Algorithm Hyperacute: - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
neurocognitive disease
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
of underlying disease
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
coronary artery disease
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