Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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diagnosis hematology differential rheumatology syndrome cardiology oncology atrial fibrillation thrombosis venous activation afib agglutinin algorithm amyloid amyloidosis anemia antinxp2 antinxp2dm
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... aneurysm: Causes arterial ... - TMA: TTP - Arterial ... : - Behcet disease ... Diagnosis #clots #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Disease ... - Idiopathic monoclonal ... malignancy (CLL) - Monoclonal ... Such As: • IgM monoclonal ... hemolytic #anemia #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis vs Arterial ... Myeloproliferative disease ... Fat Emboli ARTERIAL ... THROMBOSIS Arterial ... pathophysiology #hematology
Atrial Fibrillation Overview Symptoms: Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope. 1. Why? Cardiac: • Valvular heart disease •
Atrial Fibrillation ... Valvular heart disease ... Structural heart disease ... : • Pulmonary disease ... Fibrillation #Cardiology #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... Inflammatory eye disease ... : Arterial (MCC-small ... : monoclonal TNF-aIpha ... Syndrome #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... • Heavy Chain disease ... Amyloidosis and monoclonal ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
10 mm + pus • Material ... inflammatory skin disease ... Sneddon-Wilkinson disease ... Pustular skin disease ... Differential #Diagnosis #Dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... gangrenosum • Bacterial ... #nonpalpable #dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
with autoimmune diseases ... including retinal arterial ... to medium-sized arteries ... of associated disease ... #rheumatology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... Granulomatous disease ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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