Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Thrombosis vs Arterial ... Fat Emboli ARTERIAL ... THROMBOSIS Arterial ... in all cases of arterial ... pathophysiology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... malignancy (CLL) - Monoclonal ... Such As: • IgM monoclonal ... chills, flank pain ... hemolytic #anemia #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... aneurysm: Causes arterial ... - TMA: TTP - Arterial ... , HUS, DIC #Arterial ... Diagnosis #clots #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... abnormal intact monoclonal ... : • Serum IgM monoclonal ... MGUS: • Serum monoclonal ... #Significance #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Schönlein purpura • PAN ... Sarcoidosis #dermatology ... #joint #pain #skin
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
10 mm + pus • Material ... neutrophils) • Pus --> bacterial ... Bacterial folliculitis ... with rheumatic pain ... Differential #Diagnosis #Dermatology
Atrial Fibrillation Overview

Symptoms:
Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

1. Why?
Cardiac:
• Valvular heart disease
•
Atrial Fibrillation ... intolerance, chest pain ... Anticoagulation #Atrial
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Causes of Leg Pain ... Patellofemoral pain ... Causes of Leg Pain ... ulcers, Edema Arterial
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint Pain ... Noninflammatory Pain ... at night Pain ... virus • Rubella Bacterial ... gonorrhea) • Bacterial