Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... status NTM Cause ... Bone Marrow - Anemia ... patients with typical tuberculosis ... differential #diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Mycobacterium tuberculosis ... ), anemia, arthralgia ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Leukocytosis, anemia ... hemorrhage • Treatment ... #differential #causes
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
associated with infection ... by bacterial infections ... (90%), Fungal infections ... subdural hematoma, lung ... Otalgia #Ear #Pain #Otology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Disorders: • Infection ... (tuberculosis, ... fungal infections ... ) - Tuberculosis ... Adrenals: • Lung
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework

IATROGENIC DISEASE
Secondary to invasive cardiac procedures

NONIATROGENIC
• Malignancy (e.g., metastatic spread:
metastatic spread: lung ... • Hemorrhagic tuberculous ... with pulmonary tuberculosis ... OTHER RARE CAUSES ... amyloidosis • Uremia
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
schistosomiasis • Pyemia ... Causes: • Still's ... • Disseminated tuberculosis ... Yellow fever • Tuberculous ... Brucellosis • Liver or lung