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aki
diagnosis
nephrology
differential
algorithm
acutekidneyinjury
causes
injury
kidney
pathophysiology
acute
azotemia
cancer
classification
druginduced
electrolytes
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Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg) Assess Volume Status, Check Urine Na, Urine Osm #Hyponatremia #Algorithm #Diagnosis #Nephrology #Differential #Hypotonic
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron #DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS - Nephrotoxins (NSAlDs, contrast, OTCs, herbals, abx, illicits, chemo, immunosuppression) - Hx of AKI/CKD - Recent hypo/hypertension? - TTE/liver fxn? - BMP, cap, CBC w/ diff - Urinalysis/microscopy/UOP/weights - Urine Na/K/Cl/urea/protein/Cr - Renal/bladder US w/ PVR - CPK, uric acid (rhabdo/TLS) Causes of Inpatient AKI (Liano 1996) - ATN - 45% - Pre-renal disease — 21% - AKI on CKD— 13% (mostly ATN and pre-renal) - Urinary tract obstruction — 10% (most often prostate related) - Glomerulonephritis or vasculitis — 4% - Atheroemboli — 1% #AcuteKidneyInjury #AKI #Nephrology #Diagnosis #Algorithm #Causes #Differential
Algorithmic Approach to the Patient with Azotemia #Azotemia #AKI #Nephrology #Diagnosis #Differential #Algorithm #Management
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast • Lymphomatous infiltration • Light chain (LC) cast nephropathy • LC deposition disease (LCDD) • Heavy chain DD • Proximal LC tubulopathy • Monoclonal gammopathy of renal significance (MGRS) • Secondary Membranous nephropathy • Solid tumors • Secondary Minimal change disease • Hematologic malignancies Treatment Related • Sepsis, volume depletion • Hepatic sinusoidal obstructive syndrome • Capillary leak syndrome (Interleukin-2) • Tumor lysis syndrome • Proximal tubular injury • Cisplatin • ATN: Imatinib, ifosfomide • Crystal nephropathy: Methotrexate • AIN: Sorafenib, sunitinib , PD-Ii • TMA: Gemcitabine, cisplatin, bevacizumab (VEGFi), TKi • Hemorrhagic cystitis -> bladder outlet obstruction (cyclophosphamide) #Acute #Kidney #Injury #AKI #Cancer #Oncology #Differential #Diagnosis #Classification #Nephrology
Urine Electrolyte Interpretation - AKI, Hyponatremia, Hypokalemia and Non-Gap Metabolic Acidosis #Urine #Electrolytes #Interpretation #ULytes #AKI #FENa #FEUrea #Nephrology #Diagnosis
HepatoRenal Syndrome - Pathophysiology Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ #HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis #Nephrology #AKI
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease 1) Tubule and interstitium 2) Vasculature 3) Glomerulus Dr. Pablo Galindo @galindozip #Renal #Kidney #Syndromes #Differential #Diagnosis #Causes #Failure #Injury #AKI
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