Pathnologic @pathnologic
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Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... with extensive rouleaux ... #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... (blood). ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... wherein normal blood ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... Smear #Peripheral #Pathology ... #Microscopy #Clinical ... #Blood
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
#neutrophils #BoneMarrow ... #Smear #Hematology ... #Pathology #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... hemolytic #anemia #Hematology ... #Pathology #Smear
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
#PlasmaCells #BoneMarrow ... #Clinical #Pathology ... #Hematology
Peripheral blood smear of a patient with tick bite and PCR positive for Ehrlichia ewingii.

Ehrlichia ewinqii
Peripheral blood ... Smear #Morulae #Hematology ... #Pathology #Microscopy ... #TickBite #Clinical