Pathnologic @pathnologic
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Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils ... AML #Clinical #Hematology ... #Pathology #Smear
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
Megaloblastic neutrophils ... Megaloblastic #neutrophils ... #BoneMarrow #Smear ... #Hematology #Pathology
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... Parvovirus #Pathology #Smear ... #Microscopy #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... over-represented in primary plasma ... formation #Clinical #Smear ... #Hematology #Pathology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
BM core, most plasma ... to identify as plasma ... #PlasmaCells #BoneMarrow ... Clinical #Pathology #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... Pathology #Blood #Smear ... Rouleaux #Formation #Hematology