Pathnologic @pathnologic
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Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils ... #AML #Clinical ... #Hematology #Pathology
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
Megaloblastic neutrophils ... Megaloblastic #neutrophils ... #BoneMarrow #Smear ... #Hematology #Pathology ... #Clinical
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
extensive rouleaux formation ... leukemia #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... Smear #Microscopy #Hematology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
#PlasmaCells #BoneMarrow ... #Clinical #Pathology ... #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... #Clinical #Pathology ... Microscopy #Rouleaux #Formation ... #Hematology