Pathnologic @pathnologic
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Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
mucosal-dominant Pemphigus ... mucosal #dominant #Pemphigus ... Pathology #Microscopy #Dermatology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... Smear #Microscopy #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... over-represented in primary plasma ... Clinical #Smear #Hematology
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
good example of Pemphigus ... SGottesmanMD #Pemphigus ... Pathology #Microscopy #Dermatology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
BM core, most plasma ... to identify as plasma ... Clinical #Pathology #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... Rouleaux #Formation #Hematology