Pathnologic @pathnologic
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Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
CD138 helps (same ... #Myeloma #CD138 ... #PlasmaCells #BoneMarrow ... #Clinical #Pathology ... #Hematology
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... #Parvovirus #Pathology ... Smear #Microscopy #Hematology ... #Clinical
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
mucosal-dominant Pemphigus ... mucosal #dominant #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology ... #Clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... over-represented in primary plasma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
#neutrophils #BoneMarrow ... #Smear #Hematology ... #Pathology #Clinical
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
good example of Pemphigus ... SGottesmanMD #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology ... #Clinical
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... #Clinical #Pathology ... Rouleaux #Formation #Hematology