Pathnologic @pathnologic
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Dysplasia in Myelodysplastic Syndrome 
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Dysgranulopoiesis 
 - Dyserythropoiesis 
 - Dysmegakaryopoiesis 

#Dysplasias #MDS #Myelodysplastic
Myelodysplastic Syndrome ... #Dysplasias #MDS ... Myelodysplastic #Syndrome ... #Pathology #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... Kyle Bradley, MD ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Smear #Microscopy #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
Kyle Bradley, MD ... #neutrophils #BoneMarrow ... #Smear #Hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Genevieve Crane, MD ... Clinical #Pathology #Hematology
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
Silvija Gottesman MD ... Pathology #Microscopy #Dermatology
Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization.
Silvija Gottesman MD ... Pathology #Microscopy #Dermatology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Genevieve Crane, MD ... Clinical #Smear #Hematology
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Silvija Gottesman MD ... Pathology #Microscopy #Dermatology