Pathnologic @pathnologic
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Dysplasia in Myelodysplastic Syndrome 
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Dysgranulopoiesis 
 - Dyserythropoiesis 
 - Dysmegakaryopoiesis 

#Dysplasias #MDS #Myelodysplastic
Myelodysplastic Syndrome ... Myelodysplastic #Syndrome ... #Pathology #Hematology
Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization.
cytoplasmic trichohyalin granules ... Trichodysplasia #spinulosa #Pathology ... #Microscopy #Dermatology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... leukemia #APL #APML #Pathology ... #Hematology #Clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Cells #Clinical #Pathology ... Smear #Microscopy #Hematology
Dubin-Johnson Syndrome - A laparoscopic exploration revealed a smooth liver with normal consistency and morphologic features
Dubin-Johnson Syndrome ... deep-brown, pigmented granules ... B) #Clinical #Pathology ... #DubinJohnson #Syndrome ... #Microscopy #NEJM
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
like it has a granular ... Pemphigus #Vulgaris #Pathology ... #Microscopy #Dermatology
Pigmented Macule - A Skin Manifestation of Invasive Breast Cancer - However, a pigmented macule that
deposits of melanin granules ... Clinical #Derm #Pathology ... PigmentedMacule #Microscopy #NEJM
Cutaneous Actinomycosis - the left knee was noted to have edema, erythema, hyperpigmentation, hyperkeratinization, and several
without purulence or granule ... Clinical #Derm #Pathology ... SplendoreHoeppli #Microscopy #NEJM