Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... presence of metabolic syndrome ... include extrahepatic biliary ... LFTs #Abnormal #Algorithm
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Biliary Pain 20% ... Mirizzi's Syndrome ... Fistula/Bouveret's Syndrome
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... #PBC #Primary #Biliary ... Cirrhosis #Diagnosis #Algorithm
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
congenital - Primary biliary ... disease (Budd-Chiari syndrome
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
hepatitis - Acute biliary ... Hemochromatosis - Primary biliary
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Benign/malignant biliary ... obstruction, Primary biliary ... Injury #Diagnosis #Algorithm
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... and Management Algorithm ... functional somatic syndromes ... Irritable #Bowel #Syndrome ... Diagnosis #Management #Algorithm
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... inflammation and biliary ... #PBC #Primary #Biliary
Hepatopulmonary Syndrome (HPS) Diagnosis Algorithm
Bubble echo is the first piece of the puzzle. The nail on
Hepatopulmonary Syndrome ... HPS) Diagnosis Algorithm ... Hepatopulmonary #Syndrome ... HPS #Diagnosis #Algorithm
Causes of Small Bowel Bleeding - Differential Diagnosis
Common Causes:
 • Under age 40 years: Inflammatory Bowel
rubber bleb nevus syndrome ... Osler-Weber-Rendu syndrome ... Plummer-Vinson syndrome ... Ehlers-Danlos syndrome ... , Inherited syndromes