Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... - Hepatorenal Syndrome ... Infections #Cirrhosis ... #Pathophysiology ... #hepatology #liver
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... (Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
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Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... female-predominant disease ... of autoimmune disease ... Primary #Biliary #Cirrhosis ... #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe Acute ... hepatitis - Acute ... hepatitis - Wilson disease ... #Causes #Differential ... #Hepatology #Diagnosis
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ascites removed • Acute ... • Hepatorenal syndrome ... Indications #Management #Cirrhosis ... #treatment #hepatology
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Gallstone Diseases ... Acute Cholecystitis ... Mirizzi's Syndrome ... #differential # ... diagnosis #causes
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes of Acute ... Liver Injury #Diagnosis ... #Hepatology #Acute ... Injury #Causes #Differential
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... associated autoimmune disease ... of autoimmune disease ... Primary #Biliary #Cirrhosis ... #hepatology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... , Diagnosis and ... factors: Previous acute ... common: Food, Acute ... #Pathophysiology
Etiology and Complications of Cirrhosis

#Causes #Complications #Cirrhosis #Differential #Pathophysiology #Hepatology
Complications of Cirrhosis ... Complications #Cirrhosis ... #Differential # ... Pathophysiology ... #Hepatology