Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - ... Management Algorithm ... Upper GI bleed ... #Differential # ... Diagnosis #management #Algorithm
Lower GI Bleed - Differential Diagnosis Algorithm

 • Structural: Diverticulosis, Hemorrhoids, Post-polypectomy, Polyps & malignancy, Anal
Lower GI Bleed - ... Differential Diagnosis ... Algorithm • ... #Differential # ... Diagnosis #Algorithm
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... Diagnosis Algorithm ... • Blood loss: GI ... bleed, GU bleed ... #Diagnosis #Algorithm
Lower GI Bleed - Management Algorithm

Suspected lower GI bleeding (LGIB):
 • Hematochezia 
 • Melena +
Lower GI Bleed - ... Management Algorithm ... bleed) vs Stable ... #Bleed #LGIB #GIBleed ... #management #Algorithm
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Non-renal losses: • GI ... #Hypokalemia #Differential ... #Diagnosis #Algorithm
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... Diagnosis Workup Algorithm ... Hypovolemic (H2O loss): GI ... Hypernatremia #Differential ... Diagnosis #Workup #Algorithm
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... granular casts/RTE; blend ... Nephritis #AIN #Algorithm
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Elevated aPTT / PT - Differential ... Diagnosis Algorithm ... aPTT #PT #INR #Algorithm ... #Hematology #differential
Additional Modalities for Workup of GI Bleed (Other than EGD + Colonoscopy)

Pill endoscopy
 • Able to
for Workup of GI ... Bleed (Other than ... non-therapeutic, massive bleed ... MatthewHoMD #GI ... #Bleed #GIBleed
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Thrombocytopenia #Differential ... #Diagnosis #Algorithm