2928 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... involvement with 2 ... • hypotension 2. ... allergen with >2 ... #Anaphylaxis #pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... involvement (type 2 ... Diagnosis #Signs #Symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
disomy: inheriting 2 ... Syndrome Signs/Symptoms ... Obesity -> Type 2 ... Syndrome #genetics #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Presenilin 1 and 2 ... chromosome 21) Signs / Symptoms ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... and scarring 2. ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis #Pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Clinical Signs/Symptoms ... back pain - Symptoms ... May have signs/symptoms ... decreased reflexes Pathophysiology ... RIPE therapy for 2
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Features: • Many symptoms ... patients have no symptoms ... syndromes: (distinct symptoms ... Management #Signs #Symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... ARDS to explain symptoms ... transfusion • Pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... Clinical Signs/Symptoms ... topical steroids 2.
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
- Postulate 2 ... PolyarteritisNodosa #Pathophysiology ... Diagnosis #Signs #Symptoms