29 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... internal organs 3 ... skin thickening Signs ... and Symptoms: ... rheumatology #diagnosis #signs
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Rheumatoid Arthritis ... Rheumatoid Nodules, Pulmonary ... Disease and ILD ... #rheumatology #signs ... #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
arthritis (RA) ... erythematosus (SLE) Signs ... / Symptoms: - ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... Raynaud's phenomenon, arthritis ... Diagnose PBC if 2/3 ... gp210/sp100) 3.
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... Lung involvement 3% ... autoantibodies #signs ... #symptoms #mimickers
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... SLE, Reactive arthritis ... diagnosis #management #signs ... #symptoms #rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... , obstructive pulmonary ... Symptoms (Sx) in ... purpura: strong sign ... are proteinase 3
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... GCA (Giant Cell Arteritis ... • Progressive symptoms ... or proteinase 3