29 results
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... hematuria, mild ... proteinuria, granular casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... hematuria syndrome ... : - RBC casts ... microscopic and
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... cells on urine microscopy ... RBCs and/or RBC casts ... with polyangiitis/microscopic
Causes of Dysuria - Differential Diagnosis Algorithm
Pyuria - Leukocytes on Dipstick/Microscopy
 - Bacteriuria & Hematuria -
Differential Diagnosis Algorithm ... Leukocytes on Dipstick/Microscopy ... Bacteriuria & Hematuria ... Pyelonephritis - WBC Casts ... Leukocytes on Dipstick/Microscopy
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... #Comparison #Algorithm
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Acute increase in ... • Hepatorenal syndromes ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... but can be seen in ... suggestive of nephrotic sydnrome ... #Urine #Microscopy
Crystal cast in patient with AKI and TLS on Urine Microscopy

Randy Luciano MD, PhD @RandyLucianoMD

#TLS #Crystal
Crystal cast in ... patient with AKI ... and TLS on Urine Microscopy ... #TLS #Crystal #casts ... crystalluria #Urine #Microscopy
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... cases are caused ... Assess UA w/ microscopy ... for WBCs, RBCs, casts
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urinalysis/microscopy ... rhabdo/TLS) Causes ... Liano 1996) - ATN ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential