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diagnosis differential nephrology vasculitis acute aki classification syndromes ana antibodies antibody antineutrophil antinuclear bloodsmear borrelia clinical cryoglobulinemia cryoglobulins diseases hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... dipstick, urine microscopy ... osmolarity If cause ... • Cardio-renal syndrome ... #AKI #Workup #Algorithm
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
• Hepatorenal syndromes ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic ... #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... tract, and often causes ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... polyangiitis), MPA (microscopic ... Goodpasture's cause ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... DDX: • ANCA (Antineutrophil ... vasculitis - GPA, EGPA, microscopic ... classification #rheumatology
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Northeast Africa with cases ... Several cases have ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
)): Microscopic ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
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