16 results
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... retroorbital mass) • Microscopic ... Sjogren's syndrome ... • IgA vasculitis ... #vasculitis #differential
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... • ANCA Associated ... : - Microscopic ... Disease • Cogan syndrome ... #dermatology #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... Churg-Strauss syndrome ... drugs, malignomas, and ... Vessels #Diagnosis #Rheumatology
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... inflammation: • Microscopic ... #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... - Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... polyangiitis, Microscopic ... vasculitis, Behcet ... , anti-GBM ab, ANA ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... ): • Microscopic ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic ... #rheumatology #
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... urine sediment Microscopic ... urine sediment by microscopy ... Diagnostic of GN or vasculitis ... #Hematuria #Differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Differential Diagnosis ... dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... Abdominal compartment syndrome ... • Cardio-renal syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... cases • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... antibodies #diagnosis #rheumatology