21 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Pathology #Smear #Microscopy ... #Hematology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain hematuria syndrome ... pain + gross or microscopic ... hematuria: - RBC casts
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... heme-granular casts ... tubulointerstitial nephritis, renal ... Fatty - Nephrotic syndrome ... #Differential #Microscopy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA), microscopic ... polyangiitis without renal ... involvement - PR3>MPO Microscopic ... polyangiitis - MPO>PR3 Renal-limited ... PR3 #Diagnosis #Rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... • Hepatorenal syndromes ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Associated: - Microscopic ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Microscopic polyangiitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... polyangiitis), MPA (microscopic ... Syndromes (PRS) ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts