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differential nephrology rheumatology acute aki algorithm management pulmonary vasculitis ana antibodies antibody antineutrophil antinuclear blood bloodsmear borrelia classification clinical diseases
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Diagnosis Framework ... syndrome: • ... : - RBC casts ... Causes of Hematuria ... #causes #urology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... Antineutrophil #antibodies #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... Differential Diagnosis ... Pauci-Immune: - ANCA-positive ... polyangiitis, Microscopic ... #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Renal: - Glomerular ... membrane, Alport syndrome ... #Diagnosis #Causes ... #urology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... osmolarity If cause ... Glomerulonephritis / Vasculits: ANCA ... syndrome: troponin
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... polyangiitis), MPA (microscopic ... Auto-antibodies: ANCA ... : • U/A: microscopic ... , RBC casts, low
Approach to Microscopic Hematuria Microscopic hematuria is often incidental but may be associated with urologic malignancy.
Hematuria Microscopic ... associated with urologic ... RBC's, cellular casts ... with cystoscopy & renal ... #Microscopic #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Differential #Microscopy
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... • Hepatorenal syndromes ... Epithelial cell casts ... polyangiitis /microscopic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... pulmonary and renal ... ): • Microscopic ... tract, and often causes ... Dx: GPA, EGPA, microscopic
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